Reduced Orexin System Function Contributes to Resilience to Repeated Social Stress
نویسندگان
چکیده
منابع مشابه
Delta Opioid Receptor Signaling Promotes Resilience to Stress Under the Repeated Social Defeat Paradigm in Mice
Axe Neurosciences, Centre de Recherche du CHU de Québec—Université Laval, Québec, QC, Canada, Centre de Recherche du CHU de Sherbrooke and Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada, Département de Pharmacologie-Physiologie, Université de Sherbrooke, Sherbrooke, QC, Canada, Quebec Pain Research Network, Sherbrooke, QC, Canada, Integrated Program in...
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Depression is a severe and chronic psychiatric disease, affecting 350 million subjects worldwide. Although multiple antidepressants have been used in the treatment of depressive symptoms, their beneficial effects are limited. The soluble epoxide hydrolase (sEH) plays a key role in the inflammation that is involved in depression. Thus, we examined here the role of sEH in depression. In both infl...
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Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...
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Objective(s):Reduction of pharmacological effectiveness or tolerance appears following repeated administration of many analgesic drugs. We investigated tolerance to anti-nociceptive effects of orexin-A, an endogenous potent analgesic peptide using the hot-plate test.Materials and Methods:Orexin-A was microinjected ICV (intracerebroventricular) with an interval of 12 hr for 7 continuous days and...
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Stress is a type of person-environment relationship which is appraised by the individual as stressful or beyond one’s own resources and, as a results, threatens the individual’s wellbeing and welfare. The aim of the present study was to investigate the variables of resilience, coping strategies, and social support as predictors of vulnerability to stress among students. The participants consist...
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ژورنال
عنوان ژورنال: eneuro
سال: 2018
ISSN: 2373-2822
DOI: 10.1523/eneuro.0273-17.2018